Sodium Starch Glycolate

Sodium Starch Glycolate by Zyntex is a high-efficiency superdisintegrant used primarily in pharmaceutical tablet and capsule formulations to ensure rapid drug release and dissolution.

SKU: 9063-38-1 Category: Tags: ,
Description
Sodium Starch Glycolate is a specialized sodium salt of a carboxymethyl ether of starch, widely recognized as a “superdisintegrant” in the pharmaceutical industry. Zyntex provides high-purity Sodium Starch Glycolate (CAS 9063-38-1) designed for rapid disintegration and dissolution of oral solid dosage forms. As a modified starch derivative, it exhibits extraordinary swelling properties when in contact with water. In addition, its effectiveness is largely independent of the compression force used during tableting. Therefore, formulation scientists and pharmaceutical manufacturers utilize this excipient to enhance the bioavailability of active pharmaceutical ingredients (APIs) in both immediate and modified-release tablets.

Comprehensive Product Overview of Sodium Starch Glycolate

Exceptional swelling capacity and rapid water uptake provide a major competitive advantage in the development of fast-acting pharmaceutical formulations. This superdisintegrant works by absorbing water through capillary action, causing the starch granules to swell up to 300% of their original volume. It helps manufacturers achieve consistent disintegration times even for hydrophobic drug molecules that typically resist dissolution. For instance, Sodium Starch Glycolate is highly effective in direct compression processes where other disintegrants might fail due to high tablet hardness. Consequently, it ensures that the tablet breaks apart into primary particles quickly within the gastrointestinal tract. As a result, Zyntex ensures optimized degree of substitution and particle size distribution for our supply, ensuring maximum performance during your manufacturing cycles.

Moreover, Zyntex supplies specialized grades derived from potato starch for high-purity requirements. This compound acts as a critical aid in increasing the surface area available for drug dissolution, directly impacting the onset of therapeutic action. It pushes the boundaries of drug delivery science by being compatible with most common fillers and lubricants used in tableting. At the same time, it maintains its disintegrant efficiency even in the presence of hydrophobic lubricants like magnesium stearate. In short, our product serves as a dependable “dissolution catalyst.” It supports both the precision of pharmaceutical research and the heavy-duty requirements of large-scale drug production.

Recently, scientific interest in its application for nutraceuticals and specialized food supplements has grown. It provides a stable and non-toxic solution for improving the delivery of vitamins and minerals. Because of this, Zyntex offers refined grades designed to meet the rigorous specifications of modern health supplement manufacturing. Ultimately, choosing Zyntex secures a reliable and transparent chemical supply chain. We balance starch chemistry expertise with rigorous quality monitoring and regulatory compliance. To conclude, our commitment ensures your Sodium Starch Glycolate applications achieve the highest levels of functional performance and patient safety.

Key Industrial Applications for Sodium Starch Glycolate

This high-performance pharmaceutical excipient is essential in these four primary areas:

💊 Tablet Disintegration

Primary superdisintegrant for solid dosages. Thus, it is vital for achieving rapid break-up of tablets in the stomach.

🧬 Bioavailability Enhancement

Increases dissolution rates of APIs. Undoubtedly, it is critical for drugs with poor solubility profiles.

🍏 Nutraceuticals

Used in vitamin and mineral supplements. Consequently, it ensures effective nutrient release in dietary products.

🧪 Capsule Formulations

Acts as a filler-binder with disintegrant properties. Specifically, it aids the release of powder contents from gelatin shells.

Technical Specifications

ParameterStandard Value
Product NameSodium Starch Glycolate
Disintegration MechanismRapid Swelling (Superdisintegrant)
pH Range (Stability)3.0 – 11.0
CAS Number9063-38-1

📝 Safety & Handling: Sodium Starch Glycolate is non-toxic and biodegradable. Therefore, store in a cool, dry area in well-closed containers to protect from moisture. Use standard industrial hygiene practices, including a dust mask and gloves. Always consult the Safety Data Sheet (SDS) for detailed environmental and safety protocols.