Trimethoprim
Pharmaceutical-grade Trimethoprim (CAS 738-70-5), min. 99.0%, supplied wholesale by Zyntex to licensed human and veterinary producers. Antibacterial API used alone and with sulfonamides. CoA and SDS with every lot.
Description
Trimethoprim Product Overview
Trimethoprim (C14H18N4O3) is a white to off-white crystalline powder that is very slightly soluble in water. It is described in the USP, EP and BP.
Trimethoprim blocks a different step in the bacterial folate pathway than sulfonamides, so the two are often combined. In human medicine, it is formulated alone or with sulfamethoxazole (co-trimoxazole). In veterinary medicine, it is commonly combined with Sulfadiazine or Sulfadimidine in oral powders, solutions and injectables.
Zyntex supplies it from qualified API producers with lot-specific documentation, only to companies licensed for pharmaceutical or veterinary use. For other sulfonamide APIs, see Sulfaguanidine and Sulfanilamide.
Key Applications of Trimethoprim
Main application areas:
💊 Human Medicines
API for tablets and oral suspensions.
🐄 Veterinary Medicines
Combined with sulfonamides in powders, solutions and injectables.
🔗 Combination Products
Partner API for sulfonamide combinations.
🔬 Generic Development
Development and reference material.
Trimethoprim Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Trimethoprim |
| CAS Number | 738-70-5 |
| Molecular Formula / Weight | C14H18N4O3 / 290.32 g/mol |
| Assay / Purity | Min 99.0% |
| Appearance | White to off-white powder |
| Documents | CoA and SDS with every lot |
⚠️ Safety & Handling: Pharmacologically active substance; may be harmful if swallowed and may damage the unborn child. Avoid inhalation of dust and contact with skin and eyes; wear gloves, eye protection and dust protection. Store in tightly closed, light-resistant containers in a cool, dry place. Always consult the Safety Data Sheet (SDS) for full classification and handling instructions.
Frequently Asked Questions
Why is trimethoprim combined with sulfonamides?
It and sulfonamides block two different steps of the same bacterial pathway, so the combination is more effective than either alone.
Do you supply it for veterinary use?
Yes, to licensed veterinary pharmaceutical producers. Please state the pharmacopoeia standard when requesting a quote.
How can I get a price and documents?
Prices depend on quantity, packaging and destination. Contact us with your required volume to receive a quotation together with the CoA and SDS.
