Tacalcitol 1-hydrate
Tacalcitol 1-hydrate (Zyntex) is a synthetic Vitamin D3 analogue used in the topical treatment of psoriasis by inhibiting keratinocyte proliferation and inducing differentiation.
Description
Tacalcitol 1-hydrate Product Overview
Maximum therapeutic precision provides a major advantage in managing chronic skin conditions. Tacalcitol 1-hydrate effectively inhibits the excessive growth of skin cells that lead to plaque formation in psoriasis. This feature makes it ideal for long-term topical therapy without the high risk of systemic hypercalcemia. For instance, it is the preferred choice for treating psoriasis vulgaris due to its high receptor affinity and localized action. Consequently, it supports improved skin texture and patient comfort. As a result, Zyntex produces Tacalcitol 1-hydrate with high chemical purity, ensuring total stability in lipid-based dermatological formulations.
Moreover, Zyntex provides pharmaceutical-grade actives for advanced research in cellular differentiation and immune modulation. This application allows for the study of non-genomic Vitamin D signaling pathways in the epidermis. It pushes the boundaries of modern dermatopharmacology. At the same time, healthcare formulators value its role in developing steroid-free alternatives for sensitive skin areas. In short, our product serves as a dependable “topical D3 modulator.” It supports both the retail dermatological market and specialized clinical research solutions. Recently, interest in Tacalcitol 1-hydrate for managing vitiligo has grown, highlighting its expanding role in pigmentary disorder research.
Tacalcitol 1-hydrate Key Applications
This high-purity Vitamin D3 analogue is vital in these four specialized sectors:
🧴 Dermatology
It is the primary active for psoriasis management. Thus, it provides consistent results for reducing scaling and plaque thickness.
🧪 Skincare R&D
It serves as a key agent for studying skin barrier function. Consequently, it helps develop next-generation topical treatments.
💊 Pharma Formulation
It works as a key active for non-steroidal creams. Undoubtedly, it is essential for formulating safe, long-term skin therapies.
🔬 Clinical Trials
It acts as a primary active for comparative dermatological studies. Specifically, it aids in assessing the efficacy of VDR agonists.
Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Tacalcitol 1-hydrate |
| Assay / Purity | 98.0% – 102.0% |
| Molecular Formula | C27H44O3 · H2O |
| CAS Number | 93129-94-3 |
⚠️ Usage Note: Tacalcitol 1-hydrate is extremely sensitive to light and oxygen. Therefore, store in a tightly sealed, light-resistant container under inert gas and maintain refrigeration ($2°C$ to $8°C$) to prevent degradation.
