Naltrexone hydrochloride
Naltrexone Hydrochloride is a premium-grade, crystalline opioid receptor antagonist active pharmaceutical ingredient (API) carrying CAS number 16606-41-4. This high-purity, synthetic congener of oxymorphone is widely utilized across the global healthcare sector to manufacture clinical-strength oral tablets, extended-release capsules, and specialized formulations for alcohol and opioid dependence treatment
Description
Comprehensive Product Overview of Naltrexone Hydrochloride
Exceptional metabolic stability and rapid receptor displacement provide a major competitive advantage in the formulation of therapeutic treatments. This active pharmaceutical ingredient works by providing the essential structural mechanisms—specifically binding competitively to receptor sites to block the effects of exogenous opioids—needed for effective systemic modulation. It helps manufacturers achieve potent maintenance profiles in addiction recovery and specialized immune-modulation formulas without sacrificing formula stability. For instance, Naltrexone Hydrochloride is frequently used as a primary ingredient in clinical-strength dependency aversion setups. Consequently, it improves the final clinical efficacy of comprehensive relapse prevention and localized neuro-baseline balancing routines. As a result, Zyntex ensures low heavy metal content and strict chromatographic purity for our supply, ensuring maximum safety during your manufacturing cycle.
Moreover, Zyntex supplies specialized fine powder grades for the human clinical compounding and cutting-edge pharmaceutical industries. This compound acts as a critical structural asset, helping to enhance the direct chemical defense mechanisms of biological systems undergoing long-term therapy or compound evaluation codes. It pushes the boundaries of medical science by offering a highly stable active source that does not affect the final solution’s target properties during direct wet granulation or hard shell capsule filling. At the same time, it serves as a crucial biomaterial matrix in the synthesis of specialized low-dose naltrexone coatings and fine chemical drug intermediates. In short, our product serves as a dependable “structural matrix.” It supports both the vitality of the human body and the precision of modern biomedical engineering.
Key Industrial Applications for Naltrexone Hydrochloride
This high-purity crystalline antagonist drug salt is essential in these four primary sectors:
💊 Oral Tablets
Primary active pharmaceutical source used for compressing film-coated dependency management pills. Thus, it provides essential support for localized dosage control lines.
🧪 Low-Dose Capsules
Key drug ingredient utilized for compounding micro-dose (LDN) capsules targeted for chronic wellness profiles. Undoubtedly, it is vital for enhancing uniform compounding accuracy benchmarks.
🏥 Addiction Medicine
Used as a professional active base for manufacturing long-acting rehabilitation formulations and liquids. Consequently, it is vital for high-performance receptor stabilization controls.
🔬 Receptor Assays
Acts as an essential reference active for opioid binding studies, neurological mapping, and laboratory trials. Specifically, it supports rapid compounding and high molecule clarity.
Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Naltrexone Hydrochloride |
| Assay / Purity (HPLC) | 98.0% – 102.0% (On Dried Basis) |
| Appearance | White to off-white crystalline powder |
| Specific Optical Rotation | -187° to -197° |
| Loss on Drying | ≤ 1.0% |
| CAS Number | 16606-41-4 (Anhydrous: 16590-41-3) |
📝 Safety & Handling: Formulated strictly for controlled pharmaceutical manufacturing, clinical anti-dependency compounding, and certified laboratory workflows. Naltrexone Hydrochloride is a highly potent pharmacologically active compound. Workplace overexposure, physical contact, or fine dust inhalation can trigger unintended receptor antagonism, gastrointestinal discomfort, or transient neurological baseline changes. It is moderately sensitive to ambient moisture accumulation and intense light exposure loops, which can accelerate systemic structural degradation. Therefore, store strictly in a cool, dry, dark location below 25°C, completely protected from direct sunlight fields, atmospheric dampness, and strong incompatible oxidizing reagents in its original safety-sealed airtight containers. Mitigate fine powder suspension loops during weight allocation or formulation scales to secure workplace safety. Wearing high-grade personal protective equipment (PPE)—including chemical-resistant nitrile gloves, safety goggles, protective garments, and a certified dust respirator mask—is highly mandatory. Always consult the Safety Data Sheet (SDS) for detailed environmental protocols.
