Calcipotriol 1-Hydrate
Pharmaceutical-grade Calcipotriol monohydrate (CAS 147657-22-5), 98–102%, supplied wholesale by Zyntex to licensed producers. Highly potent vitamin D analogue API for psoriasis ointments, creams, gels and scalp solutions. CoA and SDS.
Description
Calcipotriol Product Overview
Calcipotriol monohydrate is a white to off-white crystalline powder. It is a synthetic analogue of Calcitriol that acts on the skin while having much less effect on calcium balance. Like other vitamin D compounds, it is sensitive to light, air and heat.
In addition, pharmaceutical companies use it in ointments, creams, gels and scalp solutions for psoriasis, at very low concentrations of about 50 micrograms per gram. Similarly, it often pairs with Betamethasone Dipropionate in ointments and gels. Because of the tiny amounts per gram, producers usually prepare dilute pre-mixes for uniform distribution.
It is extremely potent, so it requires contained handling. Zyntex therefore supplies it only to licensed pharmaceutical companies with appropriate high-potency capabilities.
Key Applications of Calcipotriol
Typical uses include, for example:
🧴 Ointments and Creams
API for topical products.
💧 Scalp Solutions
API for scalp formulations.
🔗 Combinations
Combined with betamethasone dipropionate.
🔬 Generic Development
Development as well as reference material.
Calcipotriol Technical Specifications
| Parameter | Standard Value |
|---|---|
| Product Name | Calcipotriol Monohydrate (API) |
| CAS Number | 147657-22-5 |
| Assay / Purity | 98.0% – 102.0% |
| Appearance | White to off-white crystalline powder |
| Storage | Cold, under inert gas, protected from light |
| Documents | CoA as well as SDS with every lot |
⚠️ Safety & Handling: Fatal if swallowed, in contact with skin or if inhaled; causes damage to organs through prolonged exposure. Handle only in contained systems, and also wear full protective equipment and respiratory protection. Store locked under inert gas at low temperature, protected from light. Always consult the Safety Data Sheet (SDS), because it contains the full classification and handling instructions.
Frequently Asked Questions
How does calcipotriol differ from calcitriol?
It acts mainly on the skin and has much less effect on calcium balance than calcitriol.
Why is it handled in contained systems?
Because it is active in microgram amounts and toxic in small doses, dust exposure must be avoided.
How can I get a price and documents?
Prices depend on quantity, packaging and destination, so please contact us with your required volume. We then send a quotation together with the CoA and SDS.
